Centers for Medicare & Medicaid Services (CMS) Issue Latest ICD-10-PCS Code for ZOLL Medical’s TherOx SSO2 Therapy


CHELMSFORD, Mass.–(BUSINESS WIRE)–ZOLL® Medical Corporation, an Asahi Kasei company that manufactures medical devices and related software solutions, announced today that the Centers for Medicare & Medicaid Services (CMS) ICD-10 Coordination and Maintenance Committee has issued a latest ICD-10-PCS code for TherOx® SuperSaturated Oxygen (SSO2) Therapy. The brand new code (5A0222C), for cardiac intra-arterial use, is effective for hospital discharges starting October 1, 2022. The code includes treatment of patients with left anterior descending ST-elevation myocardial infarction (LAD STEMI) heart attacks, which have higher mortality rates than other forms of heart attacks. SSO2 Therapy is the primary and only FDA-approved treatment that has been clinically proven to significantly reduce damage to cardiac muscle in heart attack patients after coronary angioplasty with stenting.1

SSO2 Therapy is indicated for patients who are suffering LAD STEMI — also referred to as “widowmaker” heart attacks on account of the high mortality rate — and are treated with stenting inside six hours of symptom onset. The therapy delivers high levels of dissolved oxygen at 7–10 times the conventional amount on to the damaged heart muscle immediately after the coronary artery has been successfully opened via angioplasty and stenting. Multiple clinical trials have demonstrated the efficacy of SSO2 Therapy to scale back infarct size.1,2,3

“There are literally thousands of patients annually who can profit from SSO2 Therapy,4,5 and the brand new ICD-10-PCS code is a big milestone within the evolution and external validation of that therapy,” said Christopher Barnabas, President of ZOLL Circulation. “That is a serious step toward capturing critical data and further demonstrating improved patient outcomes.”

ICD-10-PCS codes are granted by the CMS Coordination and Maintenance Committee to permit precise specification of procedures to be used in health services research, epidemiology, statistical evaluation, and administrative areas. The ICD-10-PCS is a procedure classification published by america for classifying procedures performed in hospital inpatient health care settings6 and ICD-10-PCS codes are widely utilized by hospitals to support data collection, payment, and electronic health records.

About ZOLL

ZOLL, an Asahi Kasei company, develops and markets medical devices and software solutions that help advance emergency care and save lives, while increasing clinical and operational efficiencies. With products for defibrillation and cardiac monitoring, circulation enhancement and CPR feedback, supersaturated oxygen therapy, data management, ventilation, therapeutic temperature management, and sleep apnea diagnosis and treatment, ZOLL provides a comprehensive set of technologies that help clinicians, EMS and fire professionals, in addition to lay rescuers, improve patient outcomes in critical cardiopulmonary conditions. For more information, visit

About Asahi Kasei

The Asahi Kasei Group contributes to life and living for people around the globe. Since its foundation in 1922 with ammonia and cellulose fiber business, Asahi Kasei has consistently grown through the proactive transformation of its business portfolio to fulfill the evolving needs of all ages. With greater than 40,000 employees around the globe, the corporate contributes to sustainable society by providing solutions to the world’s challenges through its three business sectors of Material, Homes, and Health Care. Its health care operations include devices and systems for acute critical care, dialysis, therapeutic apheresis, transfusion, and manufacture of biotherapeutics, in addition to pharmaceuticals and diagnostic reagents. For more information, visit

1 Stone GW, et al. Circ Cardiovasc Intervent 2009;2:366-75.

2 O’Neill WW, et al. Jour of Am Coll Cardiol. 2007;50: 5:397-405.

3 David SW, et al. Catheter Cardiovasc Interv. 2018;1–9.


5 Trends in myocardial infarction rates and case fatality by anatomical location in 4 United States communities, 1987 to 2008 (from the Atherosclerosis Risk in Communities Study). Am J Cardiol. 2013 Dec 01;112(11):1714-9)


Copyright © 2022 ZOLL Medical Corporation. TherOx and ZOLL are trademarks or registered trademarks of ZOLL Medical Corporation in america and/or other countries. Asahi Kasei is a registered trademark of Asahi Kasei Corporation. All other trademarks are the property of their respective owners.


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